Prospective evaluation of hot snare polypectomy with low power pure-cut current

Safety of hot snare polypectomy with low power pure-cut current for 10-14mm nonpedunculated colorectal adenomas: a multicenter prospective study - SECURE study

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000053779

Enrollment

770

Registered

2024-03-05

Start date

2024-03-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal adenoma

Interventions

Low-Power Pure-Cut Hot snare polypectomy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with at least one 10-14 mm non-pedunculated colorectal adenoma 2. Patients aged 20 yrs or more 3. Patients with informed consent

Exclusion criteria

Exclusion criteria: 1. Cases for which the course up to 28 days after treatment cannot be followed 2. Cases of inflammatory bowel disease and colorectal polyposis 3. Cases with blood coagulation dysfunction 4. Cases with systemic infections requiring treatment 5. Cases undergoing dialysis 6. Cases taking antithrombotic drugs for which cessation according to guidelines cannot be achieved during treatment 7. Other cases deemed inappropriate as study subjects by the researchers

Design outcomes

Primary

Measure	Time frame
Delayed bleeding rate of LPPC HSP	—

Secondary

Measure	Time frame
1. Overall delayed bleeding rate 2. Incidence of delayed bleeding not requiring hemostasis 3. Incidence of intraprocedural bleeding and perforation of LPPC HSP 4. Incidence of delayed adverse events (such as delayed perforation or unscheduled visit) excluding delayed bleeding of LPPC HSP 5. Technical success rate of LPPC HSP 6. Procedure time 7. En bloc resection rate of LPPC HSP 8. En bloc R0 resection rate of LPPC HSP	—

Measure

Time frame

1. Overall delayed bleeding rate 2. Incidence of delayed bleeding not requiring hemostasis 3. Incidence of intraprocedural bleeding and perforation of LPPC HSP 4. Incidence of delayed adverse events (such as delayed perforation or unscheduled visit) excluding delayed bleeding of LPPC HSP 5. Technical success rate of LPPC HSP 6. Procedure time 7. En bloc resection rate of LPPC HSP 8. En bloc R0 resection rate of LPPC HSP

—

Countries

Japan

Contacts

Public ContactKazunori Takada

Shizuoka Cancer Center Division of Endoscopy

ka.takada@scchr.jp055-989-5222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026