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Long-term prognosis of Steatotic Liver Disease (SLD) using quantitative magnetic resonance imaging (quantitative MRI)

Long-term prognosis of Steatotic Liver Disease (SLD) using quantitative magnetic resonance imaging (quantitative MRI) - Long-term prognosis of Steatotic Liver Disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000053755
Enrollment
1000
Registered
2024-03-01
Start date
2024-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Steatotic Liver Disease

Interventions

None listed

Sponsors

Ogaki Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1,Patients with SLD in which hepatitis C, hereditary, drug-related, or other associations have been ruled out. However, patients with SLD associated with hepatitis B, autoimmune hepatitis, and primary biliary cirrhosis shall be eligible. 2,Patients with SLD associated with hepatitis B, autoimmune hepatitis, or primary biliary cirrhosis are eligible. Patients who are currently under observation and have not had a quantitative MRI after an interval of at least one year are also included, as are patients who have obtained a new consent form and had a quantitative MRI after an interval of at least one year. 3,Patients without concurrent hepatocellular carcinoma at the time of the first quantitative MRI. However, patients who subsequently developed hepatocellular carcinoma will be included if more than one year has passed since the first quantitative MRI and the interval between the second (or more than one) quantitative MRI measurement and the first quantitative MRI measurement is more than one year. 4,Patients whose participation is deemed appropriate by the principal investigator or subinvestigator.

Exclusion criteria

Exclusion criteria: 1,Patients with claustrophobia 2,Patients with magnetic materials or tattoos on the body 3,Patients with a pacemaker 4,Patients who are judged by the principal investigator or subinvestigator to be unsuitable for the study.

Design outcomes

Primary

MeasureTime frame
Liver stiffness (liver fibrosis), the factor most strongly related to prognosis, was used as the objective variable to analyze how the degree and change of hepatic steatois and other factors are related to the progression of liver fibrosis.

Countries

Japan

Contacts

Public ContactTakashi Kumada

Gifu Kyoritsu University Faculty of Nursing

takashi.kumada@gmail.com0584773511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026