Measurement of salivary pH while chewing gum containing acidulant.

Measurement of salivary pH while chewing gum containing acidulant. - crossover single blind controlled trial- - Measurement of salivary pH while chewing gum containing acidulant.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000053667

Enrollment

Registered

2024-02-21

Start date

2024-02-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Interventions

Single intake of the gum 1 containing acidulant. Single intake of the gum 2 containing acidulant. Single intake of the gum 3 containing acidulant. Single intake of the gum 4 containing acidulant. Sing

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Males and females whose age is between 20 and 64 years old 2) Subjects who can prohibit themselves from taking alcohol on the day before trial 3) Subjects who can sleep enough on the day before trial and keep their regular conditions

Exclusion criteria

Exclusion criteria: 1) Female subjects who are pregnant or lactating, or intending to become pregnant during the study 2) Subjects who have the possibility of developing allergic symptoms by the test food 3) Subjects who have a fever or complain of illness 4) Subjects who have difficulty chewing gum ordinarily (80 times/min) 5) Subjects who have meal or snack within 1 hour before the trial starts 6) Subjects whose salivary flow late is below 1 mL/min

Design outcomes

Primary

Measure	Time frame
Salivary pH	—

Secondary

Measure	Time frame
Salivary weight	—

Countries

Japan

Contacts

Public ContactShota Sato

LOTTE Co., Ltd. Central Laboratory

satou_shouta@lotte.co.jp048-837-0187

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026