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Comparison of effects of remimazolam and propofol on mask ventilation during general anesthesia induction: a randomized controlled trial

Comparison of effects of remimazolam and propofol on mask ventilation during general anesthesia induction: a randomized controlled trial - The effects of remimazolam on mask ventilation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000053553
Enrollment
76
Registered
2024-02-07
Start date
2024-05-13
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mask ventilation during general anesthesia induction

Interventions

In the randomization unit 1, loss of consciousness during general anesthesia is performed using intravenous remimazolam. In the randomization unit 2, loss of consciousness during general anesthesia is

Sponsors

Seoul National University Bundang Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Undergoing general anesthesia for surgery

Exclusion criteria

Exclusion criteria: - Current C-spine diseases or history of c-spine surgery - Edentulous - Mechanical airway obstruction such as pharyngeal neoplasm or abscess - Morbid obese - Risk of regurgitation and pulmonary aspiration - Sleep apnea - Craniofacial anomaly - History of allergic reaction to benzodiazepine or propofol - Chronic use of opioids, benzodiazepine, or antipsychotic medications - Pregnancy - Acute narrow angle glaucoma - Myasthenia gravis - Cerebral infarction

Design outcomes

Primary

MeasureTime frame
Warters grading scale

Secondary

MeasureTime frame
Han's grading scale Vital signs during general anesthesia - heart rate - blood pressure - pulse oximeter Mallanpati score Thyromental distance Cormack-Lehane grade

Countries

Asia(except Japan)

Contacts

Public ContactJin-Woo Park

Seoul National University Bundang Hospital Department of Anesthesiology and Pain Medicine

jinul8282@gmail.com82-31-787-7499

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026