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Comparative study on jigger lotion versus potassium permanganate for the treatment of tungiasis in children in Vihiga County, Kenya

Randomised, parallel-group study to compare the efficacy of jigger lotion versus potassium permanganate for the treatment of tungiasis in children in Vihiga County, Kenya - Randomised, clinical study to compare jigger lotion versus potassium permanganate for tungiasis in children in Kenya

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000053464
Enrollment
100
Registered
2024-04-01
Start date
2024-03-04
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tungiasis

Interventions

Jigger lotion one or two times 0.05% potassium permanganate (KMnO4) solution, only once at the beginning

Sponsors

Nagasaki University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients aged three or older age with an established diagnosis of tungiasis with stage II or IIIa based on rapid assessment by Fortaleza classification, which describes flea viability signs such as pulsation of the abdomen, expulsion of eggs, and excretion of a faecal thread.

Exclusion criteria

Exclusion criteria: or more fleas, and any disability preventing active cooperation in the study and those who have received treatment four weeks before the intervention and allergic to any of the treatments studied will be excluded. The severe cases will be referred to the Subcounty or County hospital for further clinical treatment.

Design outcomes

Primary

MeasureTime frame
Treatment-induced change (improvement or deterioration) in the skin condition affected by tungiasis within 2 weeks

Secondary

MeasureTime frame
Development of adverse events/effects and symptomatic improvements within 2 weeks

Countries

Africa

Contacts

Public ContactYasuhiko Kamiya

Nagasaki University School of Tropical Medicine

ykami@nagasaki-u.ac.jp+81958197891

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026