Exploration of Optimal Thyroid Resection Range in Papillary Thyroid Carcinoma with Lateral Neck Lymph Node Metastasis

Exploration of Optimal Thyroid Resection Range in Papillary Thyroid Carcinoma with Lateral Neck Lymph Node Metastasis - OPL trial

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000053461

Enrollment

400

Registered

2024-01-27

Start date

2023-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intermediate-risk cN1b papillary thyroid carcinoma (PTC) with both primary tumors and lymph node metastases in the ipsilateral neck region

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who underwent surgery for intermediate-risk cN1b PTC with both primary tumors and lymph node metastases in the ipsilateral neck region between 2005 and 2012 at Ito Hospital.

Exclusion criteria

Exclusion criteria: Patients with PTC exhibiting high-risk factors, including (i) distant metastases, (ii) any metastatic lymph node 3 cm and over in largest dimension, (iii) T4, or (iv) incomplete tumor resection. Patients with (v) final pathology indicating non-PTC or (vi) concurrent other thyroid cancers.

Design outcomes

Primary

Measure	Time frame
Overall survival (OS)	—

Secondary

Measure	Time frame
Recurrence-free survival (RFS), Modified RFS, Any determinants of being assigned a lobectomy versus a total thyroidectomy.	—

Countries

Japan

Contacts

Public ContactYoshiyuki Saito

Ito hospital Department of Surgery

y-saito@ito-hospital.jp+81-3-3402-7411

Outcome results