Relative quantitative analysis of sperm protein expression in cases of fertilization failure by Liquid Chromatograph-Mass Spectrometry ( LC-MS/MS)

Relative quantitative analysis of sperm protein expression in cases of fertilization failure by Liquid Chromatograph-Mass Spectrometry ( LC-MS/MS) - Analysis of sperm protein expression in cases of fertilization failure by Liquid Chromatograph-Mass Spectrometry ( LC-MS/MS)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000053455

Enrollment

100

Registered

2024-02-01

Start date

2024-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility with recognized fertilization failure

Interventions

None listed

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) In vitro fertilization has a fertilization rate of 50% or more 2) Fertilization rate of less than 50% for in vitro fertilization and more than 50% for ICSI 3) Fertilization rate less than 50% with in vitro fertilization and less than 50% fertilization rate with ICSI

Exclusion criteria

Exclusion criteria: In the case of a diagnosis of azoospermia

Design outcomes

Primary

Measure	Time frame
In comparing the amount of protein expression by mass spectrometry, for the expected ratio of less than 0.2 times and more than 1.8 times, the confidence level is 95% and the interval width is 0.05.	—

Countries

Japan

Contacts

Public ContactTakashi Yamaguchi

Yamaguchi ART Clinic Reproduction

takabonver62@hotmail.com0276-45-8818

Outcome results