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Prospective Cohort study of Female Oncofertility

Prospective Cohort study of Female Oncofertility - PCOF

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000053453
Enrollment
300
Registered
2024-02-05
Start date
2024-02-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adolescent and young adult women with newly diagnosed cancer, requiring anticancer treatment

Interventions

None listed

Sponsors

Osaka General Medical Center
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Female cancer patients undergoing fertility preservation before or during anticancer treatment. 2. Ages at fertility preservation are over 18 and under 43. 3. Patients who can agree with this research.

Exclusion criteria

Exclusion criteria: 1. Patients undergoing ovarian cryopreservation. 2. Patients who are judged by the investigator to be ineligible to participate in this research.

Design outcomes

Primary

MeasureTime frame
Primary outcomes are serum antimullerian hormone at fertility preservation (baseline), 1 and 2 years later. Odds ratio, 95% CI and p value are calculated using multivariate multiple regression analysis.

Secondary

MeasureTime frame
Secondary outcomes are serum FSH level, antral follicle counts, and amenorrhea at fertility preservation (baseline), 1 and 2 years later. Odds ratio, 95% CI and p value are calculated about serum FSH level and antral follicle counts using multivariate multiple regression analysis. Odds ratio, 95% CI and p value are calculated about amenorrhea using logistic regression analysis.

Countries

Japan

Contacts

Public ContactSatoshi Kubota

Osaka General Medical Center Reproductive medicine center

satosikubota1982@gh.opho.jp06-6692-1201

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026