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Development of a diagnostic method for cardiac amyloidosis by delayed contrast imaging of myocardium using CT.

Development of a new diagnostic method for cardiac amyloidosis by delayed contrast-enhanced quantification of myocardium using single-energy CT. - Development of a diagnostic method for cardiac amyloidosis by delayed contrast imaging using single-energy CT.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000053389
Enrollment
80
Registered
2024-01-18
Start date
2024-01-18
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiac amyloidosis

Interventions

None listed

Sponsors

Fukushima Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Patients for whom a preoperative contrast CT scan for transcatheter aortic valve implantation will be performed, who can use the necessary amount of contrast media and can hold their breath for 25 to 30 seconds. (2) Patients who are at least 20 years old and less than 90 years old at the time of obtaining consent. (3) Patients who have been diagnosed with chronic myocardial infarction based on the diagnostic criteria of the Guidelines for the Diagnosis of Chronic Coronary Artery Disease and have imaging findings on delayed contrast-enhanced MRI images or cardiac nuclear medicine examinations (SPECT, PET), or who are suspected to have cardiac amyloidosis based on echocardiographic or electrocardiographic findings, or who are eligible for additional examinations in the future if imaging is necessary (iv) Patients who have agreed to participate in this study. (4) Patients who have agreed to participate in this study.

Exclusion criteria

Exclusion criteria: (1) Patients with a heart rate of 80 or more or with arrhythmia (2) Patients with a cardiac pacemaker (iii) Patients who are 90 years of age or older and are considered to have difficulty holding their breath for 25-30 seconds (iv) Patients with psychiatric disorders or psychiatric symptoms that make it difficult for them to participate in the study.

Design outcomes

Primary

MeasureTime frame
Evaluation of a diagnostic method by delayed contrast-enhanced images using single energy CT in patients with cardiac amyloidosis.

Countries

Japan

Contacts

Public ContactHirofumi Sekino

Fukushima Medical University Department of Radiology and Nuclear medicine

sekino@fmu.ac.jp0245471111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026