Preventive effects for wound infection by the irrigation with povidone-iodine saline in patients undergoing gastrointestinal surgery: A randomized controlled study

Preventive effects for wound infection by the irrigation with povidone-iodine saline in patients undergoing gastrointestinal surgery: A randomized controlled study - Preventive effects for wound infection by the irrigation with povidone-iodine saline

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000053380

Enrollment

Registered

2024-01-20

Start date

2024-01-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing open gastrointestinal surgery.

Interventions

Wound irrigation with povidone-iodine saline. Wound irrigation by saline.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing open gastrointestinal surgery.

Exclusion criteria

Exclusion criteria: Patients who are allergic to iodine. Patients who disagreed to participate in the study.

Design outcomes

Primary

Measure	Time frame
The incidence rate of postoperative wound infection.	—

Secondary

Measure	Time frame
1. Detection of remnant bacteria in the wound after wound irrigation. 2. The association between the bacteria detected in the wound and those detected in preoperatively collected feces. 3. In case of wound infection, investigate the association between the bacteria detected in the wound infection, those detected in preoperatively collected feces, and those detected in the blood collected before surgery.	—

Measure

Time frame

1. Detection of remnant bacteria in the wound after wound irrigation. 2. The association between the bacteria detected in the wound and those detected in preoperatively collected feces. 3. In case of wound infection, investigate the association between the bacteria detected in the wound infection, those detected in preoperatively collected feces, and those detected in the blood collected before surgery.

—

Countries

Japan

Contacts

Public ContactYukihiro Yokoyama

Nagoya University Graduate School of Medicine Division of Surgical Oncology, Department of Surgery

yyoko@med.nagoya-u.ac.jp0527442222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026