A study to confirm the effect of continuous ingestion of food containing bifidobacteria to improve gut microbiota

A study to confirm the effect of continuous ingestion of food containing bifidobacteria to improve gut microbiota - A study to confirm the effect of continuous ingestion of food containing bifidobacteria to improve gut microbiota

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000053378

Enrollment

Registered

2025-06-30

Start date

2024-01-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Ingestion of an enteric capsule containing bifidobacteria for 2 weeks. Ingestion of a capsule containing bifidobacteria for 2 weeks. Ingestion of an enteric capsule without bifidobacteria for 2 weeks.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy adult men and women who defecate at least five times a week. 2. Subjects who have received sufficient explanation of the purpose and content of the research, is capable of giving informed consent, voluntarily volunteers to participate in the research, and consents to participate in the research in writing.

Exclusion criteria

Exclusion criteria: 1. Subjects who regularly use intestinal or laxative drugs (including laxatives). 2. Subjects who ingested antibiotics within one month of the start of the study. 3. Heavy alcohol drinkers (consuming more than 60 g/day of alcohol) or alcoholics. 4. Subjects who regularly consume fermented milk or lactic acid bacteria beverages containing lactobacilli or bifidobacteria, and foods for specified health uses or foods with functional claims (including supplements) containing large amounts of oligosaccharides and are unable to stop during the study period. 5. Subjects who consume foods high in viable bacteria or high in dietary fiber daily and are unable to refrain from them during the examination period. 6. Subjects suffering from a disease requiring urgent treatment or those with serious complications. 7. Subjects with gastrointestinal diseases affecting digestion and absorption, or with a history of surgery. 8. Subjects with food allergies. 9. Subjects who are pregnant, intend to become pregnant during the study period, or are breastfeeding. 10. Subjects participating in a study involving the ingestion of other foods or the use of drugs.

Design outcomes

Primary

Measure	Time frame
Fecal bifidobacteria	—

Countries

Japan

Contacts

Public ContactMasashi Tsukamoto

Ezaki Glico Co., Ltd. R&D Laboratory

masashi.tsukamoto@glico.com06-6477-8352

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026