Effects of simultaneous intake of water-soluble liquid konjac and indigestible dextrin on gut microbiota composition in young women: an open-label, cross-over, before-after comparison, dose-dependent study

Effects of simultaneous intake of water-soluble liquid konjac and indigestible dextrin on gut microbiota composition in young women: an open-label, cross-over, before-after comparison, dose-dependent study - Effects of simultaneous intake of water-soluble liquid konjac and indigestible dextrin on gut microbiota composition in young women: an open-label, cross-over, before-after comparison, dose-dependent study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000053367

Enrollment

Registered

2024-01-16

Start date

2024-01-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Duration: 4 weeks. Test substance: water-soluble liquid konjac and indigestible dextrin-containing food (120 g/1 bag). Administration: 1 time/day. Duration: 4 weeks. Test substance: water-soluble l

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Healthy adults

Exclusion criteria

Exclusion criteria: 1. Food allergy (especially konjac). 2. Took antibiotics within 3 weeks of the start of this study. 3. Regularly use laxatives. 4. Diseases of the large intestine, prone to diarrhea and other gastrointestinal diseases. 5. Having or history of chronic diseases as follows, malignant tumor, heart failure, or myocardial infarction. 6. Having or history of chronic diseases as follows, cardiac arrhythmia, liver disorder, kidney disorder, cerebrovascular disorder, rheumatism, diabetes mellitus, dyslipidemia, hypertension, or any other chronic diseases. 7. Pregnant, lactating, or planning to become pregnant during this trial. 8. Participate in other clinical studies or participated in the last 28 days or plan to participate in other clinical studies. 9. Smoker. 10. BMI>30.0 or BMI<17.0.

Design outcomes

Primary

Measure	Time frame
Changes in human gut microbiota with continuous intake of test substances.	—

Secondary

Measure	Time frame
1. Subjective defecation status. 2. Body weight.	—

Countries

Japan

Contacts

Public ContactMisaki Kurawaka

Jumonji University Department of Food Science, Faculty of Human Life

m-krwk@jumonji-u.ac.jp048-477-0555

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026