Malignant disease, Cancer, Breast cancer, Hematologial disease, Leukemia, pediatric cancer
Conditions
Interventions
None listed
Sponsors
St. Marianna University School of Medicine
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Patients who have undergone ovarian tissue freezing must have received an explanation of the content of this study, fully understood it, and, in principle, obtained free written consent from the patient and their relatives, including their spouse or guardian. To be there. In cases where the patient has already died, the above-mentioned relatives must be informed and their consent obtained.
Exclusion criteria
Exclusion criteria: If the patient or family has expressed opposition to donating the tissue to research at the time of ovarian tissue freezing. If patient consent is not obtained for ovarian tissue to be performed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We will image the follicle using OCT and create a standard image. Follicle number counting by OCT (primordial follicle, primary follicle, secondary follicle, antral follicle) Correlation with ovarian histological examination, blood AMH level, and other ovarian reserve tests | — |
Secondary
| Measure | Time frame |
|---|---|
| We will also verify whether it is possible to confirm the presence or absence of malignant tumors. In cases where ovarian tissue transplantation is performed, the period until ovarian function recovers after ovarian transplantation, the number of oocytes obtained after ovarian transplantation, fertilization rate, and clinical pregnancy rate (confirmation of gestational sac) are evaluated. If animal experiments are conducted, evaluation items include ovarian function recovery rate, recovery period, number of oocytes collected, and abnormality of oocytes (a separate application will be submitted as an animal experiment). | — |
Countries
Japan
Contacts
Public ContactSEIDO TAKAE
St. Marianna University School of Medicine Obstetrics and Gynecology
Outcome results
None listed