This trial was conducted on children with cleft lip and palate that went through a corrective operation for the condition. Once the children went through the operation, all patients received standardised post-operative analgesic drugs. Additionally, patients in the intervention group received curcumin patch placed on their chest. Pain evaluation was performed immediately after the anaesthesia effect wore off, and eight hours after the placement of the curcumin patch. Pain evaluation was performe
Conditions
Interventions
The control group. Patients only received standard post-surgery drug.
First intervention group. Patients received standard post-surgery drug + curcumin patch that contains piperine
Second intervention
Sponsors
Faculty of Dentistry, University of Padjadjaran
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Aged 36 months old or less; - Had an initial pain score of (a minimum of) 1 (according to the FLACC pain score); - Not allergic to curcumin and or piperine and - Did not have any injuries or inflammation at other areas of the body that might act as another source of pain. - Willing to participate
Exclusion criteria
Exclusion criteria: Participants were excluded from the study if: - participants consumed another analgesic agent aside from the ones prescribed or - participants removed the patch (those who were assigned to the treatment groups) before eight hours of application,
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The decrease of pain level through PGE2 saliva level measurement | — |
Secondary
| Measure | Time frame |
|---|---|
| The decrease of pain level through Face, Leg, Activity, Cry and Consolability (FLACC) scale scoring | — |
Countries
Asia(except Japan)
Contacts
Public ContactTantry Maulina
University of Padjadjaran, Bandung, Indonesia Oral Surgery Department, Faculty of Dentistry
Outcome results
None listed