Comparison of effects of target-controlled infusion of remifentanil and sufentanil on intraoperative blood pressure variability during video assisted thoracic surgery

Comparison of effects of target-controlled infusion of remifentanil and sufentanil on intraoperative blood pressure variability during video assisted thoracic surgery - The effects of sufentanil on video assisted thoracic surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000053293

Enrollment

Registered

2024-01-15

Start date

2024-01-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IV general anesthesia for video assisted thoracic surgery

Interventions

In the intervention group, intraoperative pain management is performed using target-controlled infusion of sufentanil. In the intervention group, intraoperative pain management is performed using tar

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - ASA (American Society of Anesthesiologists) class I-II - Lung cancer - VATS lobectomy

Exclusion criteria

Exclusion criteria: - Bilobectomy or pneumonectomy - Bilateral procedure - Chronic pain disease - Regular use of analgesics or opioids - Psychiatric disorder - Regular use of psychotropic drugs - Renal or hepatic failure - A history of allergy to opioids or any other drug used in the study

Design outcomes

Primary

Measure	Time frame
- Average Real Variability (ARV) of mean arterial pressure	—

Secondary

Measure	Time frame
- Postoperative pain using visual analogue scale (VAS, 0-10): 30 min, 2 hours, 6 hours, 24 hours after the procedure - The accumulated dose of pain killer: at 30 min, 2 hours, 6 hours, 24 hours after the procedure - The satisfaction of postoperative pain management using visual analogue scale (VAS, 0-10): at 6 hours and 24 hours after surgery - Postoperative nausea and vomiting: the accumulated dose of anti-emetic drugs for 24 hours after surgery	—

Measure

Time frame

- Postoperative pain using visual analogue scale (VAS, 0-10): 30 min, 2 hours, 6 hours, 24 hours after the procedure - The accumulated dose of pain killer: at 30 min, 2 hours, 6 hours, 24 hours after the procedure - The satisfaction of postoperative pain management using visual analogue scale (VAS, 0-10): at 6 hours and 24 hours after surgery - Postoperative nausea and vomiting: the accumulated dose of anti-emetic drugs for 24 hours after surgery

—

Countries

Asia(except Japan)

Contacts

Public ContactJin-Woo Park

Seoul National University Bundang Hospital Department of Anesthesiology and Pain Medicine

jinul8282@gmail.com82-31-787-7499

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026