The efficacy of modified Thoracoabdominal nerves blocks through perichondrial approach (M-TAPA) and External Oblique Intercostal block (EOIB) in laparoscopic cholecystectomy: single-blind randomized controlled trial

The efficacy of modified Thoracoabdominal nerves blocks through perichondrial approach (M-TAPA) and External Oblique Intercostal block (EOIB) in laparoscopic cholecystectomy: single-blind randomized controlled trial - The efficacy of modified Thoracoabdominal nerves blocks through perichondrial approach (M-TAPA) and External Oblique Intercostal block (EOIB) in laparoscopic cholecystectomy: single-blind randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000053274

Enrollment

Registered

2024-01-15

Start date

2022-12-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparoscopic cholecystectomy

Interventions

TAP block was administered bilaterally after the induction of anesthesia before the surgical procedures. M-TAPA was administered bilaterally after the induction of anesthesia before the surgical proce

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: This prospective, single-blind, randomized controlled study was conducted from December 2022 to September 2023 at single center. After providing written informed consent, patients with American Society Anesthesiologists (ASA) physical status clasification scores of I or II were included in this study.

Exclusion criteria

Exclusion criteria: The exclusion criteria were known allergy to local anesthetics, body mass index(BMI) >35 kg/m2 or <17 kg/m2, advanced liver or kidney failure,history of trauma, stroke or cognitive impairment, and chronic analgesic drugs use.

Design outcomes

Primary

Measure	Time frame
The primary outcome of the study was to evaluate the numerical rating scale (NRS) score at rest and during movement in the first postoperative 0, 1, 6, 12, and 24 hours in patients with TAPB, M-TAPA, or EOIB.	—

Secondary

Measure	Time frame
Secondary endpoints were postoperative narcotic consumption, evaluating the postoperative patient-completed QoR-15 questionnaire, the incidence of nausea and vomiting(PONV), and incidence of complications during nerve block techniques.	—

Countries

Japan

Contacts

Public ContactHideki Matsuura

Nara medical university Department of anesthesiology

hmatsura0610@naramed-u.ac.jp+81-744-29-8902

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026