Optimizing flow rate of high-flow nasal cannula using peak inspiratory flow during spontaneous breathing trial for post-extubation pediatric populations

Optimizing flow rate of high-flow nasal cannula using peak inspiratory flow during spontaneous breathing trial for post-extubation pediatric populations - Optimizing flow rate of high-flow nasal cannula using peak inspiratory flow during spontaneous breathing trial for post-extubation pediatric populations

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000053260

Enrollment

Registered

2024-01-20

Start date

2024-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pediatric patient

Interventions

1. After confirming that the SBT initiation criteria are met, thoraco-abdominal movement is measured with respiratory inductive plethysmography using two elastic transducers placed around the thorax a

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Infant under 2 years old who has undergone invasive ventilation for more than 24 hours Body weight between 2 kg and 15 kg Scheduled for SBT (Spontaneous Breathing Trial) before extubation Potential indications for HFNC (High-Flow Nasal Cannula) after extubation (Requires oxygen administration when SpO2 < 95%, breathing frequency > 60 breaths per minute, abnormal breathing patterns such as retractive breathing or paradoxical breathing, respiratory insufficiency from cardiac surgery)

Exclusion criteria

Exclusion criteria: Difficulty fitting HFNC (nasal congestion, facial trauma, intolerance) Difficulty fitting transducer (trunk trauma, burns, intolerance) Combination of HFNC with NO inhalation therapy Hemodynamic instability (mean blood pressure: <40 mmHg in neonates, <50 mmHg in infants) Severe hypoxemia (PaO2: Partial pressure of arterial oxygen/FiO2 ratio <150 in non-cyanotic heart disease) Severe acidemia (pH < 7.20)

Design outcomes

Primary

Measure	Time frame
Phase angle We collect data during SBT before extubation and during HFNC at different flow settings after extubation.	—

Countries

Japan

Contacts

Public ContactTaiga Itagaki

Tokushima University Hospital Emergency and Disaster Medicine

tigerusan@gmail.com088-631-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026