N/A (Healthy adults)
Conditions
Interventions
Intake the test food (capsules containing myricetin and luteolin) for 12 weeks
Intake the control food (capsules without myricetin and luteolin) for 12 weeks
Sponsors
Kyowa Trial Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Japanese males and females between the age 20-<65 Y at the time of filing the written consent 2)Healthy individuals who are not currently undergoing treatment for any serious disease 3)Those who have a BMI 23.0-<30.0 at screening 4)Those who have a blood LDL-cholesterol level between 120 and 139. 5)Those who are able to visit the designated facility on the scheduled visit date 6)Those who had provided written consent after fully understanding the purpose and content of this study
Exclusion criteria
Exclusion criteria: 1)Those who have difficulty to participate in this study because of conditions i.e., liver, kidney, or cardiac disease, breathing, endocrinology, metabolism, nervous, or conscious disorder, diabetes (determined by JDA), and other diseases 2)Those with history of cardiovascular diseases 3)Those who take drugs to improve glucose metabolism, lipid metabolism, or blood pressure 4)Those who regularly took medicines and/or health foods/supplements that could affect the outcomes of this study (including foods for specified uses (FOSHU), foods with functional claims (FFC), and foods with nutrient function claims (FNFC))(however, this did not apply to those who could discontinue the intake of such products at the time of providing consent) 5)Those with allergies associated with the test foods 6)Those who have been diagnosed with familial hyperlipidemia 7)Those who had experienced feeling unwell or deterioration of physical condition due to blood collection in the past 8)Those who had donated 200 mL or more blood from the earlier three month scheduled for the study or have plan to do so during the study period 9)Those who are currently participating in another clinical study or participated in another clinical study within the last four months 10)Excessive alcohol drinkers and heavy smokers 11)Those with highly irregular dietary habits 12)Those who wish to become pregnant, are pregnant women (including those who may become pregnant), or lactating mothers during the study period 13)Those who did not agree with the purpose of this study when it was explained to them earlier 14)Those who thought that the study doctor assigned is not qualified enough to evaluate for this study results
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LDL-cholesterol and amount of change | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)HDL-cholesterol and amount of change 2)Total cholesterol and amount of change 3)Triglycerides and amount of change 4)Body weight and amount of change 5)Body fat ratio and amount of change 6)BMI and amount of change 7)Waist circumference and amount of change 8)Hip circumference and amount of change | — |
Countries
Japan
Contacts
Public ContactMegumi Takahashi
Ryusendo Co., Ltd. Development Division
Outcome results
None listed