A multicenter prospective cohort study for investigating the visuality of palisade vessels at the gastroesophageal junction (GOJ) after acid secretion inhibitor in patients with reflux esophagitis

A multicenter prospective cohort study for investigating the visuality of palisade vessels at the gastroesophageal junction (GOJ) after acid secretion inhibitor in patients with reflux esophagitis - GOJ-P

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000053184

Enrollment

Registered

2023-12-21

Start date

2024-01-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reflux esophagitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients aged more than 20 years 2) Patients who were diagnosed as reflux esophagitis in the pilot studies 3) Patients who do not take vonoprazan 20mg/day 4) Patients who will take vonoprazan 20mg/day for more than four weeks and will undergo oesophagogastroduodenoscopy after administration of vonoprazan for more than four weeks 5) Patients who enrolled the pilot studies within one month 6) Patients in whom a written consent can be obtained

Exclusion criteria

Exclusion criteria: 1) Patients who do not want to undergo oesophagogastroduodenoscopy 2) Patients who are judged as inappropriate for participating in this study by the researchers

Design outcomes

Primary

Measure	Time frame
Improvement rate of endoscopic score after administration of vonoprazan 20mg/day for more than four weeks (rate of patients in whom endoscopic score increased more than one after administration of vonoprazan compared with that before administration)	—

Countries

Japan

Contacts

Public ContactShiko Kuribayashi

Gunma University Hospital Department of Gastroenterology and Hepatology

shikokuri@gunma-u.ac.jp0272-220-8137

Outcome results