Mild cognitive impairment due to non-Alzheimer'
Conditions
Interventions
Study subjects will receive exercise therapy at home under remote supervision and management. As a general rule, this will be conducted three times a week in a year.
Sponsors
Osaka University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) 65 years of age or older (2) Patient is diagnosed with mild cognitive impairment after a visit to our outpatient neuropsychology clinic of the Department of Neurology and Psychiatry. (3) CSF biomarkers or the results of amyloid PET scan indicate that the patient does not have Alzheimer's pathology. (4) Having a family member living with them or a caregiver who can visit them.
Exclusion criteria
Exclusion criteria: (1) Patients who do not have or cannot establish a reliable Internet environment at home (2) Patients for whom exercise therapy is considered contraindicated (3) Patients who have difficulty pedaling the exercise bike used for exercise therapy due to other diseases or pain (4) Patients who have difficulty operating the application due to visual or hearing impairment (5) Patients who have had hypotension, fatal arrhythmia, or other adverse events during rehabilitation, exercise stress tests, or exercise therapy (6) Patients with acute myocardial infarction leaving untreated significant (>75%) coronary artery stenosis in [AHA classification: #1,2,3,5,6,7,11,13] in the major three branches (7) Patients with end-stage heart failure (8) Patients with evidence of residual myocardial ischemia (9) Patients with poorly controlled heart failure (10) Patients after implantation of left ventricular assist device (11) Patients with a pacemaker, ICD, or implantable cardiac monitor (12) Patients whose prognosis is expected to be within 6 months (13) Patients who have participated in other clinical trials or clinical studies involving interventions within the past 12 weeks of obtaining consent (14) Patients who are judged by the investigators to be incapable of properly understanding the significance of the research and complying with the compliance requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ratio of progression to dementia after 1-year exercise therapy. | — |
Countries
Japan
Contacts
Public ContactTakashi Suehiro
Osaka University Department of Psychiatry
Outcome results
None listed