N/A (Healthy adults)
Conditions
Interventions
Test food: One g of granule dextrin contained 40 mg of non-live bifidobacteria powder (more than 0.5 x 10^10 non-live cells per 1 g of the test food) Administration: Oral intake of test food twice a
Sponsors
Meiji Co., Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Healthy females of 20 to 40 years age 2. Subjects with more than 4 measurable teeth in the 6 index teeth (teeth nos. 16, 21, 24, 36, 41, and 44) or substitutional neighboring teeth (teeth nos. 17, 15, 11, 22, 25, 37, 35, 31, 42, 45) 3. Subjects without undergoing treatment for caries or periodontal disease 4. Subjects with more than 20 teeth 5. Subjects giving written informed consent
Exclusion criteria
Exclusion criteria: 1. Subjects with severe caries or periodontal disease 2. Subjects with removable dentures 3. Subjects who have took in antibiotic or antibacterial agent within the last month to the screening test 4. Pregnant, possibly pregnant during this study, or lactating women 5. Subjects with sever systemic diseases affecting the results of this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Salivary IgA and IgA per mg of protein | — |
Secondary
| Measure | Time frame |
|---|---|
| Oral condition and safety | — |
Countries
Japan
Contacts
Public ContactEiji Yoshikawa
KSO Corporation Clinical Trial Management department
Outcome results
None listed