The study on predicting recurrence of first-onset major depressive disorder using resting-state functional MRI

The study on predicting recurrence of first-onset major depressive disorder using resting-state functional MRI - The study on Predicting REcurrence of first-onset major DEpressive disorder using Resting-state functional MRI (PREDERM study)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000053124

Enrollment

150

Registered

2023-12-18

Start date

2023-12-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depressive disorder

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (Whole) 1. Each participant must have a level of understanding sufficient to agree to all tests including functional MRI and examinations required by the protocol and must sign an informed consent document. 2. right handed. (Patients with MDD) 1. Participants must fulfill ICD-10 criteria for F32. 2. Currently in remission, defined as a HAM-D 17 score < 7 in 8 weeks or more. (Healthy control) 1. No current or past psychiatric disorders. 2. HAM-D 17 score < 7.

Exclusion criteria

Exclusion criteria: (Patients with major depression) 1. Patients with any clinically significant psychiatric disorder other than ICD-10 criteria for F32. 2. Patients with any organic brain disease. 3. Patients with unstable medical illness. (Healthy control) Those who have a history of treatment for mood disorder or psychotic disorder in the third degree relative.

Design outcomes

Primary

Measure	Time frame
recurrence of MDD	—

Countries

Japan

Contacts

Public ContactTomoyuki Nakamura

Kurume university school of medicine Neuropsychiatry

nakamura_tomoyuki@med.kurume-u.ac.jp+81-942-31-7613

Outcome results