Epidemiological study of intestinal permeability in patients with neurological diseases

Epidemiological study of intestinal permeability in patients with neurological diseases - Epidemiological study of intestinal permeability in patients with neurological diseases

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000053079

Enrollment

200

Registered

2023-12-18

Start date

2023-12-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neurological diseases

Interventions

After fasting for at least 12 hours, drink 10 g of lactulose and 2 g of mannitol dissolved in 250 mL of water, and collect a portion of the urine after storing it for 6 hours.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. patients with neurological disorders who are 20 years of age or older at the time consent is obtained 2. patients who have given written consent to participate in this study

Exclusion criteria

Exclusion criteria: 1. patients with galactosemia 2. patients with severe intolerance to sugar alcohols or allergy to foods containing sugar alcohols 3. patients who are taking alpha-glucosidase 4. patients who are deemed unsuitable by the physician in charge 5. patients whose consent could not be obtained

Design outcomes

Primary

Measure	Time frame
To evaluate the frequency of intestinal permeability and its association with severity and prognosis in each of neurological disease	—

Countries

Japan

Contacts

Public ContactSyuuichirou Suzuki

Division of Neurology Division of Neurology

ssuzu@sapmed.ac.jp0116112111(38210)

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026