Supervised Cardiac Rehabilitation of Patients with Angina, Nonobstructive Coronary Artery Disease, and Impaired Myocardial Flow Reserve: Quantification of Clinical Effects by 13N-Ammonia Positron Emission Tomography

Supervised Cardiac Rehabilitation of Patients with Angina, Nonobstructive Coronary Artery Disease, and Impaired Myocardial Flow Reserve: Quantification of Clinical Effects by 13N-Ammonia Positron Emission Tomography - Effects of Supervised Cardiac Rehabilitation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000053060

Enrollment

Registered

2024-10-27

Start date

2018-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with angina and nonobstructive coronary artery disease associated with coronary microvascular dysfunction

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: We included 32 consecutive patients with ANOCA and impaired MFR, assessed using 13N-ammonia myocardial perfusion PET at our heart center, between November 2018 and November 2022.

Exclusion criteria

Exclusion criteria: The myocardial perfusion PET examinations, assessments of symptomatic status using the Seattle Angina Questionnaire (SAQ)-77 and exercise capacity using cardiopulmonary exercise testing (CPX), were conducted at baseline and 5-month follow-up for all study patients. Three patients refused these follow-up visits and were excluded.

Design outcomes

Primary

Measure	Time frame
Effect of 5-month exercise-based cardiac rehabilitation on PET-derived MFR, symptomatic status, and exercise capacity in patients with ANOCA.	—

Countries

Japan

Contacts

Public ContactShiro Miura

Sapporo Kojinkai Memorial Hospital Department of Cardiology,

s.miura@sap-kojk.jp011-665-0020

Outcome results