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Cognitive Behavioral Therapy as an Intervention to Prevent Weight Rebound post Semaglutide Discontinuation

Cognitive Behavioral Therapy as an Intervention to Prevent Weight Rebound post Semaglutide Discontinuation - REBOUND-STOP

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000053018
Enrollment
40
Registered
2024-01-01
Start date
2024-02-02
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Interventions

Intervention details: Subjects were divided into two groups. Group 1 received no intervention, and in addition to nutritional guidance (once a month) and exercise guidance (once a month) as a regular

Sponsors

kansai medical university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who meet all of the following criteria are eligible. 1) Patients who are 18 years of age or older at the time of obtaining consent 2) Outpatient/Inpatient, OutpatientO 3) Gender, Any 4) BMI is 27 kg/m2 or more 5) Complicated by hypertension or dyslipidemia 6) Those who are about to start drug treatment with semaglutide. 7) Those who meet the semaglutide package insert. Despite diet,exercise therapy, sufficient effects are not obtained and Have two or more obesity-related health disorders. 8) Patients who have received sufficient explanation and consent of their own free will to participate in this study with full understanding.

Exclusion criteria

Exclusion criteria: Patients who fall under any of the following will not be included in this study. 1) Patients with severe hepatic or renal dysfunction 2) Pregnant and lactating women 3) Patients with malignant tumor 4) Patients with severe heart failure/arrhythmia 5) Patients with secondary obesity due to endocrine (hormone) or other drugs, etc. 6) Patients with a history of hypersensitivity to semaglutide 7) Patients with diabetic ketoacidosis, diabetic coma or precoma, type 1 diabetes 8) Severe infections in patients with type 2 diabetes, conditions requiring emergency surgery, etc. 9) Other patients deemed unsuitable as research subjects by the research director

Design outcomes

Primary

MeasureTime frame
Weight change rate from discontinuation of semaglutide to 24 weeks after discontinuation

Countries

Japan

Contacts

Public ContactKAZUHISA TAKAHASHI

kansai medical university Department medicine II

takakazu@hirakata.kmu.ac.jp81(0)72-804-0101

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026