Healthy adult volunteers with a fasting blood glucose level in the normal range or the boundary range (less than 126 mg/dL) are included. Those who are planning to become pregnant, expectant or nursing mothers, and breastfeeding women are excluded.
Conditions
Interventions
None listed
Sponsors
Association for Salacia Promotion
Review team Mr. Kenji Ikeda (reviewer A), Fujifilm Corporation Dr. Eriko Kishino (reviewer D), Tokyo Metropolitan Technology Research Institute Ms. Ruka Yugawa (reviewer B), Morishita Jintan Co.,Ltd. Research Collaborator Professor Hiroharu Kamioka (HK), Tokyo University of Agriculture Ms. Mari Makishi (MM), Toho University, Librarian Ms. Satoko Sayama (SS), Librarian
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Systematic literature search will be performed using databases for scientific articles, clinical trials, and systematic reviews, as well as handsearching. Inclusion criteria as follows: Participants (P): Healthy adult volunteers with a fasting blood glucose level in the normal range or the boundary range (less than 126 mg/dL) are included. Those who are planning to become pregnant, expectant or nursing mothers, and breastfeeding women are excluded. Intervention (I): Intake the foods (tablets, granules, beverages, processed foods) containing Salacia-derived salacinol. The lower limit of Salacia-derived salacinol is 0.02 mg/dose. Comparison (C): Intake the foods not containing Salacia-derived salacinol. Outcome (O): The primary outcome will measure the effect on blood glucose levels after eating carbohydrates or carbohydrate-containing meals. Specifically, the postprandial blood glucose level and the area under the blood glucose curve (AUC). Both outcomes will be evaluated comprehensively. Study design (S): Adopt randomized, quasi-randomized, and non-randomized controlled trials (parallel-group or crossover trials).
Exclusion criteria
Exclusion criteria: Studies that do not meet the inclusion criteria, such as intervention trials without a placebo group, are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will measure the effect on blood glucose levels after eating carbohydrates or carbohydrate-containing meals. Specifically, the postprandial blood glucose level and the area under the blood glucose curve (AUC) of postprandial blood glucose. Both outcomes will be evaluated comprehensively. | — |
Countries
Japan
Contacts
Public ContactKoji Kimura
Association for Salacia Promotion Office
Outcome results
None listed