Prospective observational study on the association between imaging, histopathology, bacteriology, surgical technique and course of treatment in cases of Medication-related Osteonecrosis of the jaw.

Prospective observational study on the association between imaging, histopathology, bacteriology, surgical technique and course of treatment in cases of Medication-related Osteonecrosis of the jaw. - Prospective observational study on the association between imaging, histopathology, bacteriology, surgical technique and course of treatment in cases of Medication-related Osteonecrosis of the jaw.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000052956

Enrollment

Registered

2024-01-20

Start date

2023-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

medication-related osteonecrosis of the jaw

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (i) Patients aged 18 years and over undergoing surgery under general anaesthesia at MRONJ (ii) Patients who visited our oral surgery department between the date of approval by the director of the research institute and 31 March 2025 (iii) Patients for whom IC was obtained from the patient or a surrogate.

Exclusion criteria

Exclusion criteria: (i) Patients with a small extent of resection (e.g. removal of putrefied bone) (ii) Other patients deemed inappropriate as research subjects by researchers and others.

Design outcomes

Primary

Measure	Time frame
Imaging findings (CT, MR, SPECT-CT) Histopathological findings Bacteriological findings by Real-time PCR Outcome	—

Countries

Japan

Contacts

Public ContactMitsunobu Mitsunobu

Nagasaki University Hospital Oral and Maxillofacial surgery

m-ohnuma@nagasaki-u.ac.jp095-819-7698

Outcome results