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Cerebrospinal fluid dynamics visualization study using MRI

CSFMAP - CSFMAP

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000052929
Enrollment
50
Registered
2023-11-28
Start date
2020-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with hydrocephalus, syringomyelia, or arachnoid cysts who are attending or being admitted to facilities participating in this study, including the Department of Neurosurgery, Juntendo University Hospital, and those with normal spinal fluid circulation with headache, unruptured cerebral aneurysm, minor head injury, or minor stroke will be included.

Interventions

Perform MRI on normal subjects and patients with spinal fluid circulation disorders to collect and analyze information on cerebrospinal fluid physiology.

Sponsors

Juntendo University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Age between 20 and 80 years old at the time of obtaining consent. (2) After receiving a thorough explanation of the study, the subject of the research has given his/her free and voluntary written consent based on a thorough understanding of the study.

Exclusion criteria

Exclusion criteria: Those who generally cannot undergo MRI (1) Patients with claustrophobia (2) Those who cannot maintain rest in the MRI machine (3) Those who will have magnetic metals inserted into the body (iv) Those who have a pacemaker or other device inserted in the body (5) Other subjects who are deemed inappropriate as research subjects by the principal investigator.

Design outcomes

Primary

MeasureTime frame
To investigate the causes of these diseases, MRI scans will be performed on patients with normal and those with CSF circulation disorders to collect information on CSF physiology. We will analyze CSF circulation information in each region of the cerebrospinal cord cavity using MRI in patients with normal and in patients with CSF circulation disorders by applying the improved time-slip method sequence to CSF, and develop temporal sequences with up-date.In order to clarify how CSF moves within the ventricles in response to head movement, we attempted to optimize its MRI visualization.

Countries

Japan,North America

Contacts

Public ContactMADOKA NAKAJIMA

Juntendo University Neurosurgery

madoka66@juntendo.ac.jp0338133111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026