Study on the usefulness of Carbonic Anhydrase I (CA I) protein in patients with ulcerative colitis and its effect on the intestinal microbiota.

Study on the usefulness of Carbonic Anhydrase I (CA I) protein as an enteritis biomarker in faeces and colonic tissue from patients with ulcerative colitis and its effect on the intestinal microbiota. - UC-CA1 Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000052851

Enrollment

150

Registered

2023-11-20

Start date

2023-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative colitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Ulcerative and non-ulcerative colitis patients scheduled for colonoscopy

Exclusion criteria

Exclusion criteria: When a research subject declines to participate in research or withdraws consent. If it is found after enrolment that the subject does not meet eligibility criteria. If the study as a whole is discontinued If the research physician decides that it is appropriate to discontinue the research

Design outcomes

Primary

Measure	Time frame
To determine whether CA I can be a biomarker for ulcerative colitis.	—

Secondary

Measure	Time frame
To determine the role of CA1 protein, which increases or decreases in the gut of patients with ulcerative colitis, during enteritis (in relation to the gut microbiota and faecal metabolites).	—

Countries

Japan

Contacts

Public ContactMirai Hayashi

Ehime University Graduate School of Medicine Department of Gastroenterology and Metabology

3naika@m.ehime-u.ac.jp0899605308

Outcome results