A multicenter prospective cohort study for determining the optimal condition of observation for gastroesophageal junction (GOJ) in Upper esophagogastroduodenoscopy (EGD) under conscious situation

A multicenter prospective cohort study for determining the optimal condition of observation for gastroesophageal junction (GOJ) in Upper esophagogastroduodenoscopy (EGD) under conscious situation - GOJ-A

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000052827

Enrollment

500

Registered

2023-11-17

Start date

2023-11-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients in whom GOJ zone will be observed in upper EGD under conscious situation. (2) Patients have received sufficient explanation about their participation in this study and have given informed consent written by themselves.

Exclusion criteria

Exclusion criteria: (1) Patients who refuse for participating in this study (2) Patients with a history of surgical resection in upper gastrointestinal tract (3) Patients who underwent endoscopic treatment in the GOJ zone (POEM, including balloon dilatation) (4) Patients with suspected or present neoplastic lesions in the GOJ zone (5) Patients with a confirmed diagnosis of esophageal motor dysfunction such as achalasia (6) Patients who are judged as inappropriate for participating in this study by the researchers

Design outcomes

Primary

Measure	Time frame
Rate of identification for DEPV visibility between under natural breathing and deep-inspirate breathing	—

Secondary

Measure	Time frame
Differences of identification of DEPV between patients with and without hiatal hernia in each with natural breathing and deep-inspirate breathing Differences of identification of DEPV between patients with and without reflex esophagitis in each with natural breathing and deep-inspirate breathing Differences of identification of DEPV between patients with and without Helicobacter pylori infection in each with natural breathing and deep-inspirate breathing Differences of identification of DEPV depending on the degree of endoscopic gastric atrophy in each with natural breathing and under deep-inspirate breathing Difference in DEPV visibility score between natural breathing and deep-inspirate breathing Difference of PEGF visibility rate between natural breathing and deep-inspirate breathing Concordance rate of DEPV and PEGF in each with natural breathing and deep-inspirate breathing Intraobserver and interobserver agreement for visibility of DEPV Factors associated with difficulties of identification of DEPV	—

Measure

Time frame

Differences of identification of DEPV between patients with and without hiatal hernia in each with natural breathing and deep-inspirate breathing Differences of identification of DEPV between patients with and without reflex esophagitis in each with natural breathing and deep-inspirate breathing Differences of identification of DEPV between patients with and without Helicobacter pylori infection in each with natural breathing and deep-inspirate breathing Differences of identification of DEPV depending on the degree of endoscopic gastric atrophy in each with natural breathing and under deep-inspirate breathing Difference in DEPV visibility score between natural breathing and deep-inspirate breathing Difference of PEGF visibility rate between natural breathing and deep-inspirate breathing Concordance rate of DEPV and PEGF in each with natural breathing and deep-inspirate breathing Intraobserver and interobserver agreement for visibility of DEPV Factors associated with difficulties of identification of DEPV

—

Countries

Japan

Contacts

Public ContactTakashi Ueno

Jichi Medical University Department of Medicine, Division of Gastroenterology

m05012tu@jichi.ac.jp+81285587348

Outcome results