Sustained lung inflation (SLI) right after birth to decrease the use of mechanical ventilation of preterm infants is controversial because of potential harm.
Conditions
Interventions
Intervention: Sustained Lung Inflation (SLI) with 20 cm H2O for 15 sec was conducted by experienced staff in the eonatal Intensive Care Unit (NICU) between 30 min and 24 h after birth.
Control: No SLI
Sponsors
Chang Gung Memorial Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Preterm infants (with a gestational age of 27 to 35 weeks) who required CPAP to provide positive end-expiratory pressure with or without intermittent positive pressure ventilation in the NICU of Chang Gung Memorial Hospital at Taipei were eligible for enrollment.
Exclusion criteria
Exclusion criteria: Neonates with pneumothorax or a major congenital anomaly (including severe congenital heart disease), and referral neonates who had been admitted to another NICU for more than 1 day.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Use of mechanical ventilation | — |
Secondary
| Measure | Time frame |
|---|---|
| sepsis, intraventricular hemorrhage (IVH), periventricular leukomalacia (PVL), necrotizing enterocolitis (NEC), patent ductus arteriosus (PDA), retinopathy of prematurity (ROP), BPD, pneumothorax, and mortality | — |
Countries
Asia(except Japan)
Contacts
Public ContactYi-Hao Weng
Chang Gung Memorial Hospital at Taipei Pediatrics
Outcome results
None listed