Comparison of Moisturizing Effects of Emollients and Commercial Moisturizers

A Comparative Study of Transepidermal Water Loss and Stratum Corneum Hydration before and after Application of Petroleum Jelly and Commercial Moisturizers - Petroleum jelly and commercial moisturizers Application's effect on transepidermal water loss and stratum corneum hydration (PAE trial)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000052790

Enrollment

Registered

2023-11-13

Start date

2023-11-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult

Interventions

Intervention Group: (1) PIGEON Baby Milk Lotion Moisture Plus (Pigeon Corporation) Control Group: White petroleum jelly: Baby Vaseline (Kenei Pharmaceutical Co., Ltd.) Intervention Group: (2) Johns

Johnson) Control Group: White petroleum jelly: Baby Vaseline (Kenei Pharmaceutical Co., Ltd.) Intervention Group: (3) Nivea Skin Milk Moist (Nivea Kao Corporation) Control Group: White petroleum jel

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Individuals who are 20 years of age or older. 2. Individuals who have given informed consent to participate in this research by signing a consent form.

Exclusion criteria

Exclusion criteria: Individuals with obvious wounds at the intended application site.

Design outcomes

Primary

Measure	Time frame
Comparison of transepidermal water loss and stratum corneum hydration before and 2 hours after application of petroleum jelly to the left inner forearm and a commercial moisturizer to the right inner forearm.	—

Secondary

Measure	Time frame
(1) Comparison of the levels of transepidermal water loss and stratum corneum hydration before and at 1, 3, and 4 hours after application of petroleum jelly to the inner left upper arm versus a commercial moisturizer to the inner right upper arm. (2) Comparison of transepidermal water loss and stratum corneum hydration before and at 1, 3, and 4 hours after application of three different commercial moisturizers to the inner right upper arm. (3) Comparison of comfort levels associated with the application of different moisturizers using a Likert scale.	—

Measure

Time frame

(1) Comparison of the levels of transepidermal water loss and stratum corneum hydration before and at 1, 3, and 4 hours after application of petroleum jelly to the inner left upper arm versus a commercial moisturizer to the inner right upper arm. (2) Comparison of transepidermal water loss and stratum corneum hydration before and at 1, 3, and 4 hours after application of three different commercial moisturizers to the inner right upper arm. (3) Comparison of comfort levels associated with the application of different moisturizers using a Likert scale.

—

Countries

Japan

Contacts

Public ContactShuka Aono

Kyorindo Co., Ltd. P-one plaza tenno store

aonoshuka@gmail.com053-465-7431

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026