Effects of transcranial direct current electrical stimulation to the left ventrolateral prefrontal cortex on frustration-induced aggression modulation -A double-blind randomized controlled trial-

Effects of transcranial direct current electrical stimulation to the left ventrolateral prefrontal cortex on frustration-induced aggression modulation -A double-blind randomized controlled trial- - Effects of transcranial direct current electrical stimulation to the left ventrolateral prefrontal cortex on frustration-induced aggression modulation

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000052785

Enrollment

Registered

2023-11-15

Start date

2023-12-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Anodal transcranial direct current electrical stimulation to the left ventrolateral prefrontal cortex Cathodal transcranial direct current electrical stimulation to the left ventrolateral prefrontal c

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Right-handed healthy adults 2. No history of psychiatric or neurological disorders 3. A person who signed written informed consent

Exclusion criteria

Exclusion criteria: 1. Neurological findings that interfere with the performance of tasks 2. History of developmental disabilities or psychiatric disorders 3. Metal (except titanium) or electrical implants in the brain or skull 4. Metal or electronic devices in the body(e.g,pacemakers, metal remnants from trauma) 5. History of head trauma or organic disease resulting in loss of consciousness 6. History of epileptic seizures or convulsions 7.Pregnant or possibility of pregnant

Design outcomes

Primary

Measure	Time frame
1. Aggressiveness Assessment Tools(Competitive reaction-time task)	—

Secondary

Measure	Time frame
1. Heart rate 2. skin conductance 3. Japanese version of the Buss-Perry Aggression Questionnaire (Trait hostility)	—

Countries

Japan

Contacts

Public ContactDaisuke Sawamura

Faculty of Health Sciences, Hokkaido University Rehabilitation Science

D.sawamura@pop.med.hokudai.ac.jp0117063387

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026