Healthy male volunteers
Conditions
Interventions
Capsules containing 508 mg propolis were given daily for 4 weeks, and whole-body energy expenditure, respiratory quotient and adiposity were measured by indirect calorimetry at a resting state and aft
Sponsors
Hokkaido University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Those with body mass index from18.5 to 30.0 2. Those who provided informed consent forparticipation
Exclusion criteria
Exclusion criteria: 1. Those who are receiving treatment, whether seasonal, chronic, or acute, by medication, therapy, or treatment 2. Those who have a history of asthma 3. Those who are allergic to bee products (such as honey), conifers, poplar, peruvian balsam (a resin obtained from pine trees in South America), or salicylic acid (included in anti-inflammatory medicines, therapeutics for wart, corn, etc.) 4. Those who will be taking other dietary supplements during the study period 5. Those who deemed ineligible by the Principal Investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cold-induced thermogenesis (difference in oxygen consumption at room temperature of 27 degree and 19 degree) as an index of brown fat activity | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Change in body fat mass (2) Change in body surface temperature during cold exposure (3) Change in core body temperature during cold exposure (4) Changes in the degree of fatty acid oxidation and carbohydrate oxidation | — |
Countries
Japan
Contacts
Public ContactYuko Okamatsu
Hokkaido University Faculty of Veterinary Medicine
Outcome results
None listed