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Randomized Controlled Trial of an Intervention using Genetic Information and AI Health App for People with Elevated Blood Pressure

Randomized Controlled Trial of an Intervention using Genetic Information and AI Health App for People with Elevated Blood Pressure - CALO mama Plus RCT

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000052685
Enrollment
311
Registered
2023-12-18
Start date
2024-09-17
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

The intervention group will be notified that they have the salt-sensitive genotype and required to record their daily diet in &quot
CALO mama Plus.&quot
In addition, information and quiz on salt reduction will be distributed for the intervention group. The control group (1) will receive no intervention. The control group (2) will be required to record
CALO mama Plus,&quot
but information and quiz on salt reduction will not be distributed. To consider the effect of simply using the app, an auxiliary comparison between the intervention group and control group (2) will be

Sponsors

Kyoto University
Lead Sponsor
TOSHIBA CORPORATION, Wellmira Inc.
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Persons between 20 and 65 years of age - Those with angiotensinogen gene polymorphism (AGT M235T) - Those who have an elevated blood pressure (systolic blood pressure 120 or higher, or diastolic blood pressure 80 or higher) in a health checkup during 2022FY or 2023FY - Those who have not used "CALO mama Plus" before - Those who submitted urine and responded to the questionnaire before the intervention

Exclusion criteria

Exclusion criteria: - Pregnant or nursing mothers - Those who cannot use "CALO mama Plus" because they do not have a smartphone (iPhone or Android) - Those who cannot understand Japanese - Consenters whom the investigators deem inappropriate as subjects of the study

Design outcomes

Primary

MeasureTime frame
Salt intake

Secondary

MeasureTime frame
Health awareness, systolic and diastolic blood pressure, and body mass index

Countries

Japan

Contacts

Public ContactKoryu Sato

Graduate School of Medicine and School of Public Health, Kyoto University Department of Social Epidemiology

sato.koryu.8i@kyoto-u.ac.jp+81-(0)75-753-4355

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026