Patients scheduled for breast surgery under general anesthesia
Conditions
Interventions
Flumazenil group after general anesthesia
No flumazenil administered after general anesthesia group
Sponsors
Kyushu University Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Patients who meet all of the following criteria will be eligible 1. the patient has given written consent of his/her own free will 2. age between 20 and 65 years old at the time of consent 3. scheduled to undergo breast surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: Patients will be excluded from the study if any of the following apply 1) Patients with a history of hypersensitivity to remimazolam or flumazenil 2. patients with acute angle closure glaucoma, myasthenia gravis, epilepsy patients who have been receiving benzodiazepines for a long period of time, or have a history of serious complications or illnesses that would make them inappropriate for participation in this study Patients who are deemed inappropriate for inclusion in the study by the investigator. 4. (4) Patients with ASA physical status of IV or higher, shock, or coma (5) Patients with cognitive impairment 5. patients with cognitive impairment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time for 80% of patients or all patients in each group to be able to memorize. If the patient had no memory of Illustration A 1 hour after leaving the operating room, one more poster (Illustration B) was shown, and 2 hours after leaving the operating room, the patient's memory of Illustration B was checked. If the patient has no memory of Illustration B, one more poster (Illustration C) is shown, and 3 hours after leaving the operating room, the patient's memory of Illustration C is checked. If the patient remembers Illustration C, the evaluation is terminated at that point. | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Percentage of patients whose memory of the poster shown after awakening from anesthesia could be confirmed 1 hour after leaving the operating room. (2) Dosage and frequency of analgesic use from the time of return to the ward to 3 hours after surgery (3) Dosage and frequency of antiemetic use from the time of return to the ward to 3 hours after surgery | — |
Countries
Japan
Contacts
Public ContactKazuhiro Shirozu
Kyushu University Hospital Operating room
Outcome results
None listed