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Identification of new susceptibility loci for pancreatic cancer in the Japanese population

Identification of new susceptibility loci for pancreatic cancer in the Japanese population - Susceptibility loci for pancreatic cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000052651
Enrollment
105
Registered
2023-11-01
Start date
2023-09-04
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with pancreatic cancer

Interventions

None listed

Sponsors

Asahikawa Medical University
Lead Sponsor
Asahikawa-Kosei General Hospital Japanese Red Cross Asahikawa Hospital Asahikawa City Hospital Hokkaido University Hospital Teine Keijinkai Hospital Sapporo Higashi Tokushukai Hospital IMS Sapporo Digestive Disease Center General Hospital Engaru-Kosei General Hospital Nayoro City Hospital Shibetsu City Hospital Shonan Kamakura General Hospital Chibanishi General Hospital Tottori University Hospital Fujita Health University Hospital Yamagata University Faculty of Medicine Osaka
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Japanese patients with pancreatic cancer diagnosed by imaging, blood findings, or histology at Asahikawa Medical University Hospital or the collaborating institution between the date of approval and March 2029. (2) Patients must be at least 18 years old and less than 50 years old at the time of disease onset. (3) Patients or healthy volunteers who have given written consent to participate in this study. (4) Persons between the ages of 18 and 50 years old (regardless of gender) who visit Asahikawa Medical University Hospital or Sapporo Higashi Tokushukai Hospital. (5) Persons who have given written consent to participate in this study.

Exclusion criteria

Exclusion criteria: <Patients with pancreatic cancer> (1) Patients with histologically confirmed endocrine neoplasms (2) Patients with serious underlying diseases or complications that would make it difficult to participate in the study. (3) Patients who no longer meet the above selection criteria after enrollment or who are newly found to be in conflict with the exclusion criteria. (4) Patients who are judged to be inappropriate as research subjects by the physician in charge. <Volunteer> None in particular

Design outcomes

Primary

MeasureTime frame
Search for germline mutations using peripheral blood mononuclear cells (all cases).

Secondary

MeasureTime frame
(1) Frequency of detection of multiple lesions including pancreatic cysts by MRI and other imaging modalities (all cases) (2) Functional analysis of somatic mutations and drug responsiveness using primary cells in tumor tissues (in surgical cases where fresh tumor tissues can be secured prior to fixation)

Countries

Japan,North America

Contacts

Public ContactYusuke Mizukami

Asahikawa Medical University Division of Gastroenterology, Department of Medicine

mizu@asahikawa-med.ac.jp0166-68-2462

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026