Adult
Conditions
Interventions
Apply test cosmetics (combined use of lotion, essence, and cream) to whole face during 12 weeks.
Sponsors
Yamada Bee Company, Inc.
Research Center for Immunological Analysis, Inc.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Subjects who feel skin aging (wrinkle, elasticity, pores, dryness). 2) A healthy Japanese females aged 40-70 at the time of consent. 3) Subjects can understand and comply with the rules written in protocol during clinical study period. 4) Subjects whose written informed consent has been obtained.
Exclusion criteria
Exclusion criteria: The following exclusion criteria apply to subjects. 1) Constantly use cosmetic that contain the ingredient involved in this study. 2) With cosmetic allergies. 3) Visit dermatology department (for the purpose of treating atopic dermatitis etc.). 4) With inflamed or scraped skin on the measuring area. 5) Conducting hormone replacement therapy. 6) Have got cosmetic surgery which would affect the measuring area. 7) Will get sunburned during the test period. 8) Will receive special treatment (facial esthetics, epilation etc.) during the test period. 9) Can not maintain regular lifestyle. 10) Have an irregular habit because of working at night or working under work-shift form. 11) Drink more than 500 mL of beer equivalent daily. 12) Have been smoking (including electronic cigarettes) for 3 months prior to obtaining consent 13) Participated in other clinical trial within 1 month. 14) Working at the health food, cosmetics or pharmaceutical company. 15) Constantly use cosmetic, quasi-drugs, healthy foods that may affect the test. 16) Deemed inappropriate to participate in this study by the principle investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin elasticity | — |
Secondary
| Measure | Time frame |
|---|---|
| Sagging skin Water content of stratum corneum Transepidermal water loss Image analysis of facial skin Skin microbiota Skin questionnaire | — |
Countries
Japan
Contacts
Public ContactChizuru Fujikura
Yamada Bee Company, Inc. YamadaBee Company group Institute for Beauty Science, R&D department
Outcome results
None listed