schizophrenia spectrum disorder, autism spectrum disorder
Conditions
Interventions
Social cognition training plus cognitive remediation (group sessions of 1.5 hours once a week for 12 weeks)
Social cognition training plus illness management training (group sessions of 1.5 hours once
Sponsors
Kyoto University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Meet DSM-5 schizophrenia spectrum disorder and/or autism spectrum disoder criteria 2. WAIS-III estimated IQ of 65 or higher 3. Stable condiion and availability for continued participation in the study 4. Ability to communicate, read, and write in Japanese 5. Fully understand this study and provide written infromed consent
Exclusion criteria
Exclusion criteria: 1. Current substance or alcohol abuse 2. Traumatic head injury, cerebrovascular disease, or neurodegenerative disease 3. At high risk of violence, suicide attempts, or impulsive behavior
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in social cognitive functions (facial emotion recognition tasks) 12 weeks after the introduction of the intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Baseline (0w), post-intervention (12w), 12-week follow-up (24w), 1-year follow-up (64w): Social functioning (social outcome composite rating) General functioning (GAF) QOL (WHOQOL26) Clinical symptoms (SPQ, AQ, TAS-20) 0w, 12w, 24w: Neurocognition (MCCB) Clinical symptoms (BE-PSD-V2.0, CARS2-HF) Gaze behavior (eye tracking) 0w,12w: Brain imaging (structural and functional MRI) | — |
Countries
Japan
Contacts
Public ContactSadao Otsuka
Graduate School of Medicine, Kyoto University Department of Psychiatry
Outcome results
None listed