Examination of the antifatigue effect of the cacao ingredient in the commercial chocolate

Examination of the antifatigue effect iuduced by the cacao polyphenol of chocolate - Examination of the cacao polyphenol's antifatigue effect

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000052507

Enrollment

Registered

2023-10-17

Start date

2023-10-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Adult/Fatigue

Interventions

Before one hour learning, the examinees take two pieces of chocolate which is 4.65 g and contains 59mg cacao polyphenol per one piece. Before one hour learning, the examinees take two pieces of cho

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The healthy adult examinees who can take chocolate and perform one-hour learning action are targeted.

Exclusion criteria

Exclusion criteria: The examinees who cannot take in chocolate or have an allergy to chocolate and cacao are excluded.

Design outcomes

Primary

Measure	Time frame
In this experiment, physical examinations: subjective fatigue degree, blood pressure, pulse and flicker level of the examinees are measured, before the intake of chocolate. The examinees take in chocolate before learning start. After one hour learning, the same physical examinations of examinees are measured. After 30 minutes later, the same physical examinations are measured again. The examinees take two types of chocolate with different content of cacao polyphenol and perform two times of similar experiments. In this study, comparing the differences of fatigue level in each experiment, the influence of cacao polyphenol of chocolate is analyzed.	—

Measure

Time frame

In this experiment, physical examinations: subjective fatigue degree, blood pressure, pulse and flicker level of the examinees are measured, before the intake of chocolate. The examinees take in chocolate before learning start. After one hour learning, the same physical examinations of examinees are measured. After 30 minutes later, the same physical examinations are measured again. The examinees take two types of chocolate with different content of cacao polyphenol and perform two times of similar experiments. In this study, comparing the differences of fatigue level in each experiment, the influence of cacao polyphenol of chocolate is analyzed.

—

Countries

Japan

Contacts

Public ContactSeiichiro Nishida

Tezumakaya University Faculyty of Comtemporary Human Life Science

s-nishida@tezukayama-u.ac.jp0742880004

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026