Randomized Comparison Of Analgesic Efficacy Between Popliteal Plexus Block And iPACK Block After Total Knee Arthroplasty: A Noninferiority Study

Randomized Comparison Of Analgesic Efficacy Between Popliteal Plexus Block And iPACK Block After Total Knee Arthroplasty: A Noninferiority Study - Randomized Comparison Of Analgesic Efficacy Between Popliteal Plexus Block And iPACK Block After Total Knee Arthroplasty: A Noninferiority Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000052472

Enrollment

Registered

2023-10-12

Start date

2023-10-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

Popliteal Plexus Block(PPB) with 0.25% levobupivacaine 15 mL Infiltration between the popliteal artery and capsule of the knee (iPACK) block with 0.25% levobupivacaine 15 mL

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Participants aged between 18 and 85 years 2. Participants were scheduled for primary unilateral TKA for osteoarthritis 3. American Society of Anaesthesiologists Physical Status Classification I-III 4. Body mass index less than 40 kg/ m2 5. Written informed consent is provided

Exclusion criteria

Exclusion criteria: 1. Pre-existing lower limb motor dysfunction 2. Allergy to any drug administered in this study 3. Renal failure 4. Uncontrolled asthma 5. Inability to provide informed consent 6. Contraindication for peripheral nerve block 7. Coagulopathy

Design outcomes

Primary

Measure	Time frame
Incidence of moderate to severe posterior knee pain	—

Secondary

Measure	Time frame
Pain score Procedure-related date Motor and sensory assessment Opioid consumption Knee functional assessment Quality of recovery Consumption of postoperative additional analgesics Complication	—

Countries

Japan

Contacts

Public ContactTakashi Fujino

Juntendo University School of Medicine Department of Anesthesiology and Pain Medicine

t-fujino@juntendo.ac.jp+81-3-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026