Clarification of pathophysiology of motor neuron disease using neuronal excitability testing and MR Spectroscopy

Clarification of pathophysiology of motor neuron disease using neuronal excitability testing and MR Spectroscopy - Clarification of pathophysiology of motor neuron disease using neuronal excitability testing and MR Spectroscopy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000052458

Enrollment

Registered

2023-10-11

Start date

2023-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Motor neuron disease and those possible patients

Interventions

Neuronal excitability testing and MR Spectroscopy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Over 18 year old 2) Amyotrophic lateral sclerosis and those possible patients 3) Obtainment of informed consent from patients

Exclusion criteria

Exclusion criteria: 1) Patients with implement provided with a metallic portion or epilepsy, who are contraindication for transcranial magnetic stimulation 2) Patients who are contraindication for MRI 3) Patients who are judged, as inappropriate for testing, by principal investigator

Design outcomes

Primary

Measure	Time frame
Result of neuronal excitability testing and MR Spectroscopy	—

Countries

Japan

Contacts

Public ContactShibuya Kazumoto

Chiba University Department of Neurology

kazumoto@net.email.ne.jp043-226-2129

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026