Healthy Japanese subjects
Conditions
Interventions
Duration: Four weeks Test beverage: Milk beverage containing 10 billion Bifidobacterium animalis subsp. lactis GCL2505 and 5 g of inulin Administration: Take one bottle (100 g) once daily after brea
Sponsors
ORTHOMEDICO Inc.
Medical Corporation Seishinkai, Takara Clinic Nerima Medical Association, Minami-machi Clinic
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Japanese 2. Men or women 3. Subjects aged 25 or more and 60 or less 4. Healthy subjects 5. Subjects whose BMI are 25 kg/m2 or more and less than 30 kg/m2 6. Subjects with body fat percentage of 15% or more for men and 25% or more for women 7. The bottom 40 subjects with low resting metabolism among those who meet inclusion criteria No.1~6 without meeting any of exclusion criteria
Exclusion criteria
Exclusion criteria: 1. Subjects who are undergoing medical treatment or have a medical history of malignant tumor, heart failure, and myocardial infarction 2. Subjects who have a pacemaker or an implantable cardioverter defibrillator (ICD) 3. Subjects currently undergoing treatment for any of the following chronic diseases: cardiac arrhythmia, liver disorder, kidney disorder, cerebrovascular disorder, rheumatism, diabetes mellitus, dyslipidemia, hypertension, or any other chronic diseases 4. Subjects who use or take "Foods for Specified Health Uses," or "Foods with Functional Claims" 5. Subjects who are taking medications (including herbal medicines) and supplements 6. Subjects who are allergic to medicines and/or the test beverage related products 7. Subjects who are pregnant, lactating, or planning to become pregnant during this trial 8. Subjects who have been enrolled in other clinical trials within the last 28 days before the agreement to participate in this trial or plan to participate another trial during this trial 9. Subjects who have taken antibiotics within the last 28 days before the agreement to participate in this trial 10. Subjects who are judged as ineligible to participate in this study by the physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting energy expenditure at four weeks after consumption (4w) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Resting energy expenditure at two weeks after consumption (2w) 2. Respiratory quotient, energy expenditure, glucose oxidation rate, carbohydrate oxidation rate, fat oxidation rate, basal metabolic rate, body mass index (BMI), body weight, basal metabolism, body fat percentage, muscle mass, acetic acid, propionic acid, isobutyric acid, n-butyric acid, isovaleric acid, n-valeric acid, lactic acid, succinic acid, formic acid, and Bifidobacterium in the stool at 2w and 4w | — |
Countries
Japan
Contacts
Public ContactNaoko Suzuki
ORTHOMEDICO Inc. R&D Department
Outcome results
None listed