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AI-based Online Cognitive Intervention for Depression

AI-based Online Cognitive Bias Modification and Cognitive Behavioral Therapy for Depression: A Randomized Controlled Trial - AI-based Online Cognitive Bias Modification and Cognitive Behavioral Therapy for Depression

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000052394
Enrollment
160
Registered
2023-12-01
Start date
2023-12-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depressive symptoms

Interventions

Cognitive Behavioral Therapy and Cognitive Bias Modification Training (targeted at diminution of contextual memory) Cognitive Behavioral Therapy and Sham-Cognitive Bias Modification Training Waiting l

Sponsors

Kitasato University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - 18 years of age or older and less than 60 years of age - Have scored 5 or more and less than 20 points on PHQ-9 for at least one month

Exclusion criteria

Exclusion criteria: - No schizophrenia, bipolar disorder, personality disorder, substance abuse, obsessive-compulsive disorder, or mental retardation - No changes expected in pharmacotherapy during participating in the study period - No other psychotherapy received or expected to receive during the study period - No major medical illnesses - No severe cognitive deficit such as due to neurodegeneration and brain injury/trauma - No history of brain injury/trauma with loss of consciousness over 10 min - No metal or medical appliance on/inside the body - No habitual intake of excessive caffeine (> 400 mg/day) and Acetaminophen/Loxoprofen

Design outcomes

Primary

MeasureTime frame
Depressive symptoms

Secondary

MeasureTime frame
- Anxiety symptoms - Physical symptoms - Cognitive bias - Personality traits (anxiety/depression-related) - Biomarkers (including neuroimaging and endocrine/immune markers)

Countries

Japan

Contacts

Public ContactYuko Hakamata

Natinal Institute of Mental Health, National Center for Neurology and Psychiatry Department of Behavioral Medicine

cbmmri.research@gmail.com042-346-1986

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026