osteoporosis
Conditions
Interventions
Teriparatide
Abaloparatide Acetate
Sponsors
Kamagaya General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with proximal femur fracture,who comes under more than the following one of 1 items Bone density;-2.5SD or less and Vulnerable fracture Lumbar spine bone density;Less than -3.3SD Existing vertebral fracture;More than 2 Semi-quantitative evaluation method results(Existing vertebral fracture)is Grade3 Fracture of femur in the past 2.The age of the time of the agreement merit,more than 20-years old 3.The patient by whom own injection is possible 4.The patient who could get documentary consent by free will of the back and the patient person himself which had the enough explanation in case of participation of this research
Exclusion criteria
Exclusion criteria: 1.The patients with hypercalcemia 2.The patients considered to be at high risk of developing osteosarcoma 3.The patients with primary malignant or metastatic bone tumors 4.The patients with metabolic bone diseases other than osteoporosis 5.The patient with taboo Teriparatide and Abaloparatide Acetate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hip bone density variation after 18 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.At the start of treatment and after 3, 6, 12, and 18 months Bone density Hip structure analysis P1NP,TRACP-5b 2.At the start of treatment and after 6, 12, and 18 months X-ray examination Homocysteine,AGE 3.Persistence rate 4.Safety evaluation Adverse event | — |
Countries
Japan
Contacts
Public ContactTakeshi Mochizuki
Kamagaya General Hospital Plastic surgery
Outcome results
None listed