Exploratory Trial on the Psychological and Physiological Evaluation, as well as the Manifestation of Awareness through Associating Scents with Visual Images, Induced by Smell the scent of the Test Product

Exploratory Trial on the Psychological and Physiological Evaluation, as well as the Manifestation of Awareness through Associating Scents with Visual Images, Induced by Smell the scent of the Test Product - Exploratory Trial on the Psychological and Physiological Evaluation, as well as the Manifestation of Awareness through Associating Scents with Visual Images, Induced by Smell the scent of the Test Product

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000052297

Enrollment

Registered

2024-09-26

Start date

2023-09-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult female

Interventions

Smell the aroma by placing your nose close to a container filled with the test product. -

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Females aged 20 to 49 years old. 2. Subjects who use skincare products containing fragrances. 3. Subjects who have experience with esthetic treatments or similar procedures. 4. Subjects who will be without makeup on the day of the trial or are willing to remove their makeup upon arrival. 5. Subjects who can give informed consent to partake in this research, after being provided with an explanation of the protocol detail.

Exclusion criteria

Exclusion criteria: 1. Subjects who are continuously taking prescription medication as advised by a physician (over-the-counter medication is excluded). 2. Subjects with previous and/or current medical history of serious diseases in heart, liver, kidney and/or digestive organs. 3. Females who are pregnant or lactating, and females who could become pregnant or lactating during test period. 4. Subjects undergoing hormone replacement therapy. 5. Subjects who are experiencing menopausal symptoms (e.g., hot flashes, flushing, sweating). 6. Subjects who are sensitive to cold (including those who are aware of their sensitivity) 7. Subjects with dry eye syndrome. 8. Subjects with eye conditions such as exotropia, esotropia, or ptosis. 9. Subjects currently experiencing nasal congestion due to allergic rhinitis or similar conditions. 10. Subjects who have difficulty perceiving or judging scents. 11. Smokers or Subjects who have quit smoking within the last six months. 12. Subjects with a history or current diagnosis of mental illness. 13. Subjects who regularly consume large amounts of alcohol. 14. Subjects with injuries on their forehead or fingertips (first and second joints). 15. Subjects diagnosed with atopic dermatitis or exhibiting symptoms of skin disorders. 16. Subjects who feel unwell or intoxicated when smelling perfumes or fragrances. 17. Subjects who have been determined ineligible by principal investigator.

Design outcomes

Primary

Measure	Time frame
Autonomic nervous system evaluation (pupil diameter measurement, skin temperature measurement) Central nervous system evaluation (cerebral blood flow measurement)	—

Secondary

Measure	Time frame
Psychological questionnaire (SCL30, POMS2, VAS)	—

Countries

Japan

Contacts

Public ContactAyumi Yamaguchi

Mandom Corporation Advanced Technology Institute

ayumi.yamaguchi@mandom.com06-7710-1628

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026