Pediatric heart failure
Conditions
Interventions
None listed
Sponsors
Shinshu University
Aichi Children'
s Health and Medical Center Osaka Medical and Pharmaceutical University Osaka City General Hospital Kanazawa Medical University Fifu Prefectural General Medical Center Kyushu University Kyoto University Gunma Children'
s Medical Center Keio University Kobe University Saitama Prefectural Children'
s Medical Center Shizuoka Children'
s Hospital Jichi Medical University Shimane University Juntendo University Chiba Children'
s Hospital The Jikei University School of Medicine Tokyo Metropolitan Children'
s Medical Center University of Toyama Nagano Children'
s Hospital Nippon Medical School Foundation Hiroshima City Hiroshima Citizens Hospital Hokkaido University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Inpatients 2. Patients going through open heart surgery due to any diseases
Exclusion criteria
Exclusion criteria: 1. Patients under treatment of renin-angiotensin system inhibitors including type I angiotensin receptor blockers, angiotensin converting enzyme inhibitors, direct renin inhibitors, and ARNIs. 2. Patients infected with type B and C hepatitis virus or HIV. 3. Patients determined not adequate to be involved in this study by the lead principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analysis of the age-dependent expression of signaling molecules responsive to angiotensin II in the myocardium at a protein level | — |
Secondary
| Measure | Time frame |
|---|---|
| Analysis of the age-dependent expression of signaling molecules responsive to angiotensin II in the myocardium at an mRNA level | — |
Countries
Japan
Contacts
Public ContactMitsuhiko Yamada
Shinshu University School of Medicine Developmental Pharmacology Study Group
Outcome results
None listed