Healthy adult
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Subjects who are judged as healthy by self-reported health questionnaire. 2. Subjects who agree to participate in this study with a written informed consent after receiving sufficient explanation relating to this study.
Exclusion criteria
Exclusion criteria: 1. Subjects who answered in the self-reported health questionnaire that they currently have a skin disease that requires treatment. 2. Subjects who answered in the self-reported health questionnaire that they have had or are currently suffering from respiratory, gastrointestinal,hepatic/gallbladder/pancreatic, hematologic, renal, endocrine, cardiovascular and/or mental disease that requires hospital treatment. 3. Subjects who had a serious injury or surgical history within 12 weeks prior to this study. 4. Heavy smokers (more than 21 cigarettes per day), alcohol addicts (more than 80g per day alcohol), subjects who are alcohol or drug dependence, subjects who are suspected of alcohol or drug dependence. 5. Subjects who are undergoing special facial care (e.g. facial appliances, aesthetic treatments, peels, laser treatments, etc.) which would affect this study. 6. Subjects who are pregnant or lactating, or subjects who expect to be pregnant during this study. 7. Subjects who have cognitive disorder or who have possibility of the disorder. 8. Subjects who participated and took the study drug in other clinical trials within twelve weeks prior to this study. 9. Subjects who are judges as unsuitable for this study by the principal investigator or subinvestigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between Stratum corneum water content and Advanced Glycation Endproducts. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Correlation between transepidermal water loss and AGEs. 2. Correlation between skin viscoelasticity and AGEs. 3. Adverse events. | — |
Countries
Japan
Contacts
University of Miyazaki Department of Health-Care Research, University of Miyazaki(Kiyotake Branch)