Central pain modulation and analgesic effects of exercise in patients with chronic pain

Central pain modulation and effects of exercise-induced hypoalgesia in patients with chronic pain - The effects of exercise-induced hypoalgesia in patients with chronic pain

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000052265

Enrollment

Registered

2023-09-21

Start date

2023-09-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic pain

Interventions

Aerobic exercise (20 minutes)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Pain lasting more than 3 months and worst pain intensity in the past week greater than NRS 3

Exclusion criteria

Exclusion criteria: Patients with systemic inflammatory diseases, skin damage at measurement site, cognitive dysfunction that would affect the examination, and severe cerebrovascular, cardiovascular, respiratory, or metabolic diseases.

Design outcomes

Primary

Measure	Time frame
Numerical rating scale, pressure pain threshold, temporal summation of pain, and conditioned pain modulation	—

Secondary

Measure	Time frame
Central sensitization inventory, pain catastrophizing scale, hospital anxiety and depression scale, pain disability assessment scale, pain self-efficacy questionnaire, and Athens insomnia scale	—

Countries

Japan

Contacts

Public ContactTakako Matsubara

Kobe Gakuin University Graduate School of Rehabilitation

matsubar@reha.kobegakuin.ac.jp(078)974-1551

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026