healthy adult
Conditions
Interventions
Prior to the examination, structural brain data will be obtained by MRI. The intervention involves four rTMS conditions, including sham stimulation, applied to the dorsolateral prefrontal cortex using
Sponsors
Tohoku University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy adult 2. Right handed
Exclusion criteria
Exclusion criteria: 1) Individuals who have proximity to metallic objects near the stimulation site (such as cochlear implants, magnetic clips, deep brain stimulation or vagus nerve stimulation devices) or are using a cardiac pacemaker. 2) Individuals with implanted medical devices containing metal (such as internally implanted drug pumps, those using metal stents or bone replacement devices made of materials like titanium within the skull, or individuals with metal-containing dentures or implants). 3) Individuals who have a history of epilepsy or seizures. 4) Individuals taking medications that may increase the risk of seizures (such as tricyclic antidepressants, maprotiline, theophylline, methylphenidate, ketamine, clozapine, zotepine, etc.). 5) Individuals with alcohol dependence or caffeine dependence. 6) Pregnant individuals or those with severe underlying medical conditions. 7) Individuals with upper limb (hand or arm) motor impairments. 8) Individuals taking the following medications: (a) Medications to relieve symptoms such as fever, headache, or cough (anti-inflammatory pain relievers, cough suppressants, over-the-counter cold remedies, etc.). (b) Medications to alleviate nasal congestion or allergy symptoms. 9)Individuals with poor health or feeling unwell on the day of the examination
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Finger tapping speed, tempo and stability. | — |
Secondary
| Measure | Time frame |
|---|---|
| EEG 1) alpha power 2) alpha associated coherence of different cortical regions | — |
Countries
Japan
Contacts
Public ContactRyoichi Nagatomi
Tohoku University Graduate School of Biomedical Engineering
Outcome results
None listed